Kool-Aid Corner #16
To finish: trippy clippings, merry pranks, and psychedelic student life
Thumbnail image by Janjo Surace
Graph of the Week
What ‘pharmahuasca’ including DMT does to genes in rats. Positive effects were shown in the balance between reactive oxygen species cells and the anti-oxidants that keep them from becoming too ‘cytotoxic’ (damaging to other cells) and implicated in the pathogenesis of EG cancer, asthma, pulmonary hypertension, and retinopathy
Supplemental Figure 1: Heat plot for pairwise comparisons between control, predator exposure/ psychosocial stress (PE/PSS), and PE/PSS + treatment groups. The heatmap illustrates hierarchical clustering of the scaled counts (z-scores) for a set of biologically relevant differentially expressed genes (FDR<0.1).
From: Pharmahuasca and DMT Rescue ROS Production and Differentially Expressed Genes Observed after Predator and Psychosocial Stress: Relevance to Human PTSD by D Parker Kelley, Katy Venable, Aspasia Destouni, Gerald Billac, Philip Ebenezer, Krisztian Stadler, Charles Nichols, Steven Barker, Joseph Francis. Published in ACS Chemical Neuroscience Jan 2022
My bookshelf weighs a ton
Notable new purchases for the occult library. Strictly second hand snap-ups only. This week: The Science of Microdosing Psychedelics by Torsten Passie
Originally £19.99 now fetching £35-plus
Everything you need to know and considerably more from former Harvard lecturer Dr Passie. This is considered the definitive book on microdosing, the unexpected but rather popular trend for small regular doses of psychedelics.
Originally published by Psychedelic Press for superb UK public conference for the heads, Breaking Convention, this will cost you upwards of £35 on the second-hand market now.
Dr Passie includes previously untranslated international studies in his comprehensive round-up. He also tackles talking points like the placebo effect. Even if microdosing does not produce any significant effects and it is all placebo, the trend is a new way to introduce it into our society, he told a corresponding interview on the Psychedelics Today podcast.