Results Based
Medical
Does psilocybin therapy work, or not?
Kirsten Liu Wong, ‘How Fast the Shadows Fall’
Does psilocybin therapy soothe depression? The short answer is yes.
But don’t go getting all ‘salvation fantasy’ on me now.
Kick ass John Hopkins studies out earlier in 2022 claimed more than half of test subjects suffering from major depressive disorder were in remission (statistically cured) after treatment and a year later, after eight hours of prep (with Bill Richards, mind) and two doses, with five follow-up appointments. Which is… mind-blowing.
Imperial’s comparison to SSRI escitalopram ‘PsiloDep 2’ ran into some IRL type stuff when the scale it used turned out to give mediocre – well, equal – results. Other scales fared far better. But symptoms returned within three to six months. Is it fair to say that “the miracle cure thing ain’t gonna stick” as Rick ‘The Strass’ Strassman laid down in his own Vital lecture?
“Some will want longer term therapy, to understand or change things in a way that others may not”
Several patients went back to SSRIs. “For some people, psilocybin was very powerful,” says Vital lecturer Ashleigh Murphy-Beiner, who acted as a guide on the trials, “They’re quite okay with saying ‘that's enough for now’. Others lived with the symptoms of depression in a new way, probably the majority, actually, did. The psilocybin brought relief.”
NYU trial subject Court Wing defended PsiloDep 2 on Psychedelics Today, saying he “received incredible benefits – my depression of five years went completely into remission and has remained there.”
Depression is one of humanity’s worst problems, barely understood. It’s a bit consumerist of us to think somebody’s suddenly sorted it, in such a romantic fashion. For now we can only defer to the inner healer, wish godspeed to the guides, researchers, and patients, then get our Forest Passage on.
“The longer term option will be costly”
From the sharp end, Ashleigh says: “I hope all options are available to people, to work very differently with the experiences that they've had in life. Some will want longer term therapy and really get to the roots, understand or change things in a way that others people may not.
A shorter treatment or less intensive psilocybin therapy might be sufficient for them. I'm worried that the longer term option will only be available privately [not via the UK National Health Service], because it will be costly of treatment. And I'd really like the longer term treatment to be available at an affordable cost.”
Thought leaders like Dr Ros evoke 12-step-esque community circles. But, Ashleigh observes, “There’ll be a push to making shorter term treatments like we have in traditional talking therapies already now, because of budgets, and funding. The people that want to resolve aspects of their mental health experiences are disadvantaged by that.”